Paper Details
BPB Reports
Vol. 7
No. 5
p.157-159
2024
Regular Article
Colistin Potentiates the Anti-bacterial Activity of 5-O-Mycaminosyltylonolide for Some Gram-Negative Bacteria
- Yukihiro Asami (Graduate School of Infection Control Sciences, Kitasato University / Ōmura Satoshi Memorial Institute, Kitasato University / yasami@lisci.kitasato-u.ac.jp)
Aoi Kimishima
1)
2)
,
Hidehito Matsui
1)
2)
,
Yukiko Takarabe
2)
,
Masako Honsho
1)
2)
,
Paul Wasuwanich
3)
,
Sota Honma
1)
2)
,
Junsei Terai
1)
,
Hideaki Hanaki
1)
2)
,
Yukihiro Asami
1)
2)
1) Graduate School of Infection Control Sciences, Kitasato University , 2) Ōmura Satoshi Memorial Institute, Kitasato University , 3) University of Florida College of Medicine, USA
1) Graduate School of Infection Control Sciences, Kitasato University , 2) Ōmura Satoshi Memorial Institute, Kitasato University , 3) University of Florida College of Medicine, USA
Received: July 08, 2024;
Accepted: September 03, 2024;
Released: September 25, 2024
Keywords: 5-O-mycaminosyltylonolide, Antimicrobial resistance, Gram-negative bacteria, Escherichia coli, Klebsiella pneumoniae
Abstracts
We chose colistin as a new potentiator, which exhibited the relatively good potentiation activity of OMT against Escherichia coli and Klebsiella pneumoniae. This study uncovered new insight into an OMT based combination therapy.
